Product classification

130-85-8

Product Name：Pamoic acid
Molecular Formula：C₂₃H₁₆O₆
Purity：99%
Molecular Weight：

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Product Details;

CasNo： 130-85-8

Molecular Formula： C₂₃H₁₆O₆

Appearance： Fine Yellow Powder

Pamoic acid 130-85-8 Powder Supplier

Molecular Formula:C23H16O6
Molecular Weight:388.376
Appearance/Colour:Fine Yellow Powder
Vapor Pressure:2.13E-17mmHg at 25°C
Melting Point:≥300ºC (dec.)
Refractive Index:1.4593 (estimate)
Boiling Point:642.7 ºC at 760 mmHg
PKA:2.67±0.30(Predicted)
Flash Point:356.5ºC
PSA：115.06000
Density:1.499 g/cm³
LogP:4.39140

API Pamoic acid 130-85-8 Powder Usage

130-85-8 Uses

Pamoic acid is Fine Yellow Powder, while it's Molecular Formula is C23H16O6. Pamoic acid (PAM), a solubilizer commonly used in drug formulations and which is not absorbed across mucosae and by the oral route (Neubig 2010; Zhao et al. 2010).

InChI:InChI=1/C23H16O6/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h1-10,24-25H,11H2,(H,26,27)(H,28,29)/p-2

130-85-8 Relevant articles

Pamoic acid is an inhibitor of HMGB1·CXCL12 elicited chemotaxis and reduces inflammation in murine models of Pseudomonas aeruginosa pneumonia

Federica De Leo, Alice Rossi, Francesco De Marchis, Cristina Cigana, Medede Melessike, Giacomo Quilici, Ida De Fino, Malisa Vittoria Mantonico, Chantal Fabris, Alessandra Bragonzi, Marco Emilio Bianchi & Giovanna Musco

Molecular Medicine volume 28, Article number: 108 (2022)

To address pharmacological inhibition of HMGB1 with small molecules, we explored the therapeutic potential of pamoic acid (PAM), a salicylate with limited ability to cross epithelial barriers.

Structure of polymeric nanoparticles encapsulating a drug–Pamoic acid ion pair by scanning transmission electron microscopy

Natalia Koniuch, Martha Ilett, Sean M. Collins, Nicole Hondow, Andy Brown, Les Hughes, Helen Blade

Heliyon, 2023

A hydrophobic ion-pair between pamoic acid and an active pharmaceutical ingredient (API). … core of PLA and pamoic acid-API material with additional enrichment of the pamoic acid-API …

Syntheses, crystal structures and fluorescent properties of two metal-organic frameworks based on pamoic acid

GH Chen, YP He, SH Zhang, J Zhang

Journal of Solid State Chemistry, 2019

Two three-dimensional (3D) metal organic frameworks (MOFs) with pamoic acid (H 2 pam) ligand have been solvothermally synthesized, namely, [Eu 2 (pam) 3 (H 2 O) 4 ]·3EtOH·2DMF …

Crystalline cepham acid addition salts and processes for their preparation

-

, (2008/06/13)

Novel crystalline cephem acid addition salts and processes for their preparation Compounds of the formula I STR1 in which n is equal to 1 or 2 and m is 0.4-2.6, and where X is the anion of a carboxylic acid, have antibacterial activity.

130-85-8 Process route

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 92-70-6
3-Hydroxy-2-naphthoic acid

: 130-85-8
Pamoic acid

Conditions

Conditions	Yield
With sulfuric acid; In acetic acid; for 10h; Heating;	95%
With sodium hydroxide;
With sulfuric acid; acetic acid;
With sodium hydroxide;

: 9-(3-Carboxy-2-hydroxy-naphthalen-1-ylmethyl)-2,4-dioxo-4H-1,3-dioxa-2λ⁵-phospha-anthracen-2-ol anion

: 130-85-8
Pamoic acid