134-96-3
- Product Name：3,5-Dimethoxy-4-hydroxybenzaldehyde
- Molecular Formula：C9H10O4
- Purity：99%
- Molecular Weight：
Product Details;
CasNo： 134-96-3
Molecular Formula： C9H10O4
Appearance： light yellow-green to brown crystalline powder
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134-96-3 Name |
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Name |
3,5-Dimethoxy-4-hydroxybenzaldehyde |
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Synonym |
syringealdehyde;Syringylaldehyde;3,5-Dimethoxy-4-hydroxybenzaldehyde~4-Hydroxy-3,5-dimethoxybenzaldehyde;Syringaldehyde (4-Hydroxy 3,5-dimethoxybenzaldehyde);SYRINGALDEHYDE 99%;Syringealdehyde98%;Syringaldehyde, 98+%;Syringealdehyde 98% |
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134-96-3 Biological Activity |
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Description |
Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis[1]. Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 μg/mL[2]. Anti-hyperglycemic and anti-inflammatory activities[1]. |
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Related Catalog |
Signaling Pathways >> Immunology/Inflammation >> COX Natural Products >> Flavonoids Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease |
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Target |
COX-2:19.2 μM (IC50) |
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In Vivo |
Syringaldehyde exerts anti-hyperglycemic effect in rat model of diabetes induced by streptozotocin. Apart from antioxidant capability, Syringaldehyde also has anti-inflammatory activity as it is found to have inhibitory action on cyclo-oxygenase 2 (COX-2) in mouse macrophage cell line[1]. |
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References |
[1]. Shahzad S, et al. Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats. Biomed Pharmacother. 2018 Dec;108:625-633. [2]. Stanikunaite R, et al. Cyclooxygenase-2 inhibitory and antioxidant compounds from the truffle Elaphomyces granulatus. Phytother Res. 2009 Apr;23(4):575-8. |
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134-96-3 Chemical & Physical Properties |
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Melting point |
110-113 °C(lit.) |
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Boiling point |
322.1±37.0 °C at 760 mmHg |
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Density |
1.2±0.1 g/cm3 |
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Molecular Formula |
C9H10O4 |
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Molecular Weight |
182.173 |
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Flash Point |
130.1±20.0 °C |
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PSA |
55.76000 |
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LogP |
0.86 |
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Exact Mass |
182.057907 |
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Vapour Pressure |
0.0±0.7 mmHg at 25°C |
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Index of Refraction |
1.568 |
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Water Solubility |
very sparingly soluble |
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134-96-3 Description |
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Syringaldehyde is an aromatic phenolic aldehyde and a degradation product of lignin. It exhibits antioxidant activity and is reported to inhibit prostaglandin synthetase enzyme. The synthetic form of syringaldehyde is commercially used in pharmaceuticals, food, cosmetics, textiles, pulp and paper industries. |
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134-96-3 Uses |
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