28608-75-5

  • Product Name:4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-b-D-glucopyranosyl-5,7-dihydroxy-
  • Molecular Formula:C21H20O11
  • Purity:99%
  • Molecular Weight:
Inquiry

Product Details;

CasNo: 28608-75-5

Molecular Formula: C21H20O11

Appearance: yellow powder

Henan Wentao Chemical Product Co., Ltd. is a quality supplier and manufacturer of Plant Extract ORIENTIN 28608-75-5 In Medicine . You can buy high quality, low price ORIENTIN 28608-75-5 here. Contact us.

ORIENTIN 28608-75-5 Supplier

  • Molecular Formula:C21H20O11
  • Molecular Weight:448.383
  • Appearance/Colour:yellow powder 
  • Vapor Pressure:3.63E-28mmHg at 25°C 
  • Melting Point:260-285 °C 
  • Refractive Index:1.767 
  • Boiling Point:816.1 °C at 760 mmHg 
  • PKA:6.24±0.40(Predicted) 
  • Flash Point:289.1 °C 
  • PSA:201.28000 
  • Density:1.759 g/cm3 
  • LogP:-0.20270 

Plant Extract ORIENTIN 28608-75-5 In Medicine Usage

Orientin, a C-glycosyl flavonoid, is known to have anxiolytic and antioxidative activity, while it's Molecular Formula is C21H20O11. One of the bioactive compounds isolable from medicinal plants, orientin, is often used in various bioactivity studies due to its extensive beneficial properties. Orientin has been isolated from various medicinal plants such as Ocimum sanctum, Phyllostachys species (bamboo leaves), Passiflora species (passion flowers), Trollius species (Golden Queen), and Jatropha gossypifolia (Bellyache Bush).

InChI:InChI=1/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1

28608-75-5 Relevant articles

Orientin Inhibits High Glucose-Induced Vascular Inflammation In Vitro and In Vivo

SK Ku, S Kwak, JS Bae

Inflammation, 2014

In this study, we assessed whether orientin can suppress vascular inflammation induced by high glucose (HG) in human umbilical vein endothelial cells (HUVECs) and mice.

Orientin Attenuated d-GalN/LPS-Induced Liver Injury through the Inhibition of Oxidative Stress via Nrf2/Keap1 Pathway

Fuhua Li, Xia Liao, Ling Jiang, Jichun Zhao, Surui Wu, and Jian Ming*

J. Agric. Food Chem. 2022, 70, 26, 7953–7967

Orientin, a flavonoid component with antioxidant capacity, has been regarded as a promising nutraceutical for patients with liver damage. This study aimed to investigate the amelioration effect of orientin on d-galactosamine and lipopolysaccharides (d-GalN/LPS) induced liver injury in mice, with a focus on its underlying mechanisms by using the H2O2-induced oxidative damage model of HepG2 cells.

Orientin inhibits inflammation in chondrocytes and attenuates osteoarthritis through Nrf2/NF‐κB and SIRT6/NF‐κB pathway

Weiyi Xia, Jian Xiao, ChengLin Tong, Jiajie Lu, Yurong Tu, Sunlong Li, Libing Ni, Yifeng Shi, Peng Luo, Xiaolei Zhang, Xiangyang Wang

Journal of Orthopaedic Research, 25 April 2023

The natural flavonoid compound (Orientin) has anti-inflammatory bioactive properties in the treatment of various diseases. But studies have not explored whether Orientin modulates OA progression.

28608-75-5 Process route

C<sub>15</sub>H<sub>12</sub>O<sub>7</sub>

C15H12O7

UDP-glucose

UDP-glucose

isoorientin
4261-42-1

isoorientin

Luteolin-8-C-glucoside
7480-94-6,28608-75-5

Luteolin-8-C-glucoside

Conditions
Conditions Yield
With recombinant Oryza sativa C-glycosyltransferase; In ethanol; at 30 ℃; pH=7.5; Enzymatic reaction;
56%
43%
2-(3,4-bis-benzyloxyphenyl)-7-benzyloxy-8-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-5-hydroxy-4H-1-benzopyran-4-one
381686-07-3

2-(3,4-bis-benzyloxyphenyl)-7-benzyloxy-8-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-5-hydroxy-4H-1-benzopyran-4-one

Luteolin-8-C-glucoside
7480-94-6,28608-75-5

Luteolin-8-C-glucoside

Conditions
Conditions Yield
With hydrogen; palladium on activated charcoal; In ethanol; ethyl acetate; at 20 ℃;
100%

28608-75-5 Upstream products

  • 4261-42-1
    4261-42-1

    3',4',5,7-tetrahydroxy-6-C-glucopyranosylflavone

  • 131507-99-8
    131507-99-8

    2″,6″-O-diacetylorientin

  • 381686-07-3
    381686-07-3

    2-(3,4-bis-benzyloxyphenyl)-7-benzyloxy-8-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-5-hydroxy-4H-1-benzopyran-4-one

  • 39548-86-2
    39548-86-2

    1‐(2‐(benzyloxy)‐4,6‐dihydroxyphenyl)ethan‐1‐one

28608-75-5 Downstream products

  • 4261-42-1
    4261-42-1

    3',4',5,7-tetrahydroxy-6-C-glucopyranosylflavone

  • 50-99-7
    50-99-7

    D-glucose

  • 4261-42-1
    4261-42-1

    isoorientin

  • 1377947-82-4
    1377947-82-4

    orientin-2-O-β-D-galactopyranoside

Relevant Products