68-19-9

  • Product Name:Cyanocobalamin USP43
  • Molecular Formula:C63H88CoN14O14P
  • Purity:99%
  • Molecular Weight:
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Product Details;

CasNo: 68-19-9

Molecular Formula: C63H88CoN14O14P

Appearance: Crystalline

High Purity Cyanocobalamin USP43 Cas 68-19-9 Supplier

  • Molecular Formula:C63H88CoN14O14P
  • Molecular Weight:1355.44
  • Appearance/Colour:Crystalline 
  • Melting Point:>300 °C 
  • Boiling Point:>300 °C 
  • PKA:pKa 3.28±0.04(H2O,D2O t=23±0.5 Iunspeci?ed) (Uncertain) 
  • Flash Point:9℃ 
  • PSA:459.72000 
  • LogP:5.61808 

Food Additive Cyanocobalamin USP43 Cas 68-19-9 Usage

Cyanocobalamin USP43, CAS: 68-19-9, is a coenzyme for synthesis of nucleic acids and metabolism carbohydrates.

1. Cyanocobalamin USP43 deficiency can cause anemia, nervous system disorders.

2. Cyanocobalamin USP43 mainly used to treat megaloblastic anemia, poor nutrition, blood loss anemia, neuralgia and obstructive disorders.

3. As the feed nutrition fortifier, with anti-anemia effects of pernicious anemia, nutritional anemia, parasites and anemia.

4. Cyanocobalamin USP43 is essential for the metabolism of the human body. It is mainly used to treat pernicious anemia, megaloblastic anemia, antifolate drugs starting from anemia and multiple neuritis.

Vitamin B12 is Crystalline, while it's Molecular Formula is C63H88CoN14O14P.

InChI:InChI=1/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31?,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;/m1../s1/rC63H89CoN14O14P/c1-30-20-40-41(21-31(30)2)77(29-73-40)58-53(87)54(42(27-79)90-58)92-93(88,89)91-32(3)26-72-50(86)18-19-60(8)38(22-47(69)83)57-63(11)62(10,25-49(71)85)37(14-17-46(68)82)52(78(63)64-28-65)34(5)56-61(9,24-48(70)84)35(12-15-44(66)80)39(74-56)23-43-59(6,7)36(13-16-45(67)81)51(75-43)33(4)55(60)76-57/h20-21,23,29,32,35-38,42,53-54,57-58,79,87H,12-19,22,24-27H2,1-11H3,(H2,66,80)(H2,67,81)(H2,68,82)(H2,69,83)(H2,70,84)(H2,71,85)(H,72,86)(H,88,89)/q+1/p-1/b39-23+,51-33-,52-34-/t32

68-19-9 Relevant articles

Elucidating a Potential Mechanism of Permeability Enhancer Sodium N-[8-(2-hydroxybenzoyl) amino] Caprylate in Rats: Evidence of Lymphatic Absorption of Cyanocobalamin using the Mesenteric Lymph Duct Cannulated Rat

Po-Chang Chiang a, Jia Liu a, Karthik Nagapudi a, Ricky Wu a, Michael Dolton b, Jacob Chen c, Emile Plise c, Liling Liu c, Matthew R. Durk c

,Journal of Pharmaceutical Sciences Volume 111, Issue 12, December 2022, Pages 3417-3423

In this study, cyanocobalamin was used as the model compound and mesenteric lymph duct cannulated rats were used to investigate its absorption with or without SNAC. The present study demonstrated that SNAC enhanced the lymphatic absorption of cyanocobalamin when the two were co-dosed in rats. Furthermore, levels of SNAC in lymph fluid and the systemic circulation were higher when co-dosed with cyanocobalamin.

Vitamin B12 in Foods, Food Supplements, and Medicines—A Review of Its Role and Properties with a Focus on Its Stability

Ž Temova Rakuša, R Roškar, N Hickey, S Geremia

Molecules, 2022

In a narrow sense, the term vitamin B 12 implies cyanocobalamin, the anti-pernicious anemia factor isolated and crystallized in Glaxo laboratories and structurally characterized by the … 

68-19-9 Process route

methylcobalamine

methylcobalamine

2,3-dicyano-5,6-dichloro-p-benzoquinone
84-58-2

2,3-dicyano-5,6-dichloro-p-benzoquinone

vitamin B-12
68-19-9,32627-64-8,89138-85-2,41325-63-7,8039-03-0

vitamin B-12

Conditions
Conditions Yield
In ethanol; on react. of methyl cobalamine with soln. of 2,3-dichloro-5,6-dicyano-benzoquinone-(1,4) at darkness, 30min;;
30%
Cyanocobalamin (Vitamin B<sub>12</sub>)
68-19-9

Cyanocobalamin (Vitamin B12)

Conditions
Conditions Yield
Faktor V(1a) (Cobyrinsaeure-abcdeg-hexamid), < 1-α-D-Rubofuranosyl-5,6-dimethyl-benzimidazol>-3'-;
 
(Forts.) -2',3'-hydrogenphosphorsaeureester (IV) und D und/oder L-1-(benzoylcarbonylamino)-2-propanol) erhalten> (Praeparate verschiedener mikrobiol. Aktivitaet);
 

68-19-9 Upstream products

  • 84-58-2
    84-58-2

    2,3-dicyano-5,6-dichloro-p-benzoquinone

68-19-9 Downstream products

  • 13422-55-4
    13422-55-4

    CH3Cb1

  • 75-18-3
    75-18-3

    dimethylsulfide